I-Guanosine
I-Guanosine
IGuanosine isetyenziswa njengendawo ephakathi yeValaciclovir.
I-Valacyclovir liyeza le-guanine analogue antiviral.Isetyenziselwa unyango lweklinikhi ye-herpes simplex kunye nosulelo lwe-herpes zoster kwizifo ezithathelwana ngesondo.Le mveliso yi-precursor ye-acyclovir.Ifakwe ngokukhawuleza emva kokulawulwa komlomo kwaye iguqule ngokukhawuleza ibe yi-acyclovir emzimbeni.Impembelelo yayo ye-antiviral idlalwa yi-acyclovir.Emva kokuba i-acyclovir ingene kwiiseli ezinosulelo lwe-herpes, ikhuphisana ne-deoxynucleoside ye-virus thymidine deoxynucleoside kinase okanye i-cell kinase, kwaye ichiza liba ne-phosphorylated kwi-activated acyclic guanosine triphosphate.Njengesubstrate yokuphindaphinda kwentsholongwane, i-acyclovir ikhuphisana ne-deoxyguanine triphosphate ye-virus ye-DNA polymerase, ethintela ukuhlanganiswa kwe-virus ye-DNA kwaye ibonisa isiphumo sokulwa neentsholongwane.Umsebenzi we-antiviral wale mveliso kwi-vivo ungcono kune-acyclovir, kwaye isalathisi sonyango lwe-herpes simplex virus uhlobo I kunye nohlobo lwe-II luyi-42.91% kunye ne-30.13% ephezulu kune-acyclovir ngokulandelanayo.Ikwanazo nefuthe eliphezulu lokunyanga i-varicella zoster virus.
JIN DUN Medical uyeIsiqinisekiso se-ISO kwaye sidibana nemigangatho yemveliso ye-GMP, kuqeshwe iingcali zasekhaya nezangaphandle zokwenziwa kweziyobisi ezinamava atyebileyo ukukhokela iR&D yenkampani.
I-TECHNOL OGY I-ADVANTAGES
●Uxinzelelo oluPhezulu lweCatalytic Hydrogenation.Uxinzelelo oluPhezulu lwe-Hydrogenolysis Reaction.I-Cryogenic Reaction (<-78%C)
● I-Aromatic Heterocyclic Synthesis
● Ukusabela ngokutsha
● IsiGqibo seChiral
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction
Izixhobo
ILebhu yethu inezixhobo ezahlukeneyo zovavanyo kunye novavanyo, ezifana ne: NMR (Bruker 400M) ,HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, iKhalorimitha yokuSkena okwahlukileyo (DSC), iMicroscope ye-Electron...
R&D Iqela
I-Jindun Medical ineqela labasebenzi abaqeqeshiweyo be-R&D, kwaye iqeshe iingcali ezininzi zokwenziwa kweziyobisi zasekhaya nezangaphandle ukukhokela i-R&D, ukwenza udibaniso lwethu luchaneke ngakumbi kwaye lusebenze kakuhle.
Siye sanceda iinkampani ezininzi eziphezulu zamachiza zasekhaya, ezifanaHansoh, Hengrui kunye ne-HEC Pharm.Apha siza kubonisa inxalenye yazo.
Customization Case One:
Inombolo yeCas: 110351-94-5
Ityala leSibini:
Inombolo yeCas: 144848-24-8
Customization Case Three:
Inombolo yeCas: 200636-54-0
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2.Ukuphuculwa kweNkqubo yeeMveliso eziDala.Iqela lethu liya kunceda ukukhulisa nokuphucula imveliso enjalo indlela yokusabela indala, ixabiso lemveliso liphezulu, kwaye ukusebenza kakuhle kuphantsi.Sinokubonelela ngamaxwebhu apheleleyo okuhanjiswa kwetekhnoloji kunye nokuphuculwa kwenkqubo, sincede umthengi kwimveliso esebenzayo.
Ukusuka ekujoliswe kuko ngamachiza ukuya kwi-INDs, iJIN DUN Medical ikubonelelaisitophu esinye sezisombululo ze-R&D ezenzelwe wena.
I-JIN DUN Medical igxininisa ekudaleni iqela elinamaphupha, ukwenza iimveliso ezinesidima, ubuqili, ubukhali, kwaye uphume konke ukuze ube liqabane elithembekileyo kunye nomhlobo wabathengi!
