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5,6,7,7a-tetrahydrothieno(3,2-c)pyridine-2(4h)-enye ihydrochloride

5,6,7,7a-tetrahydrothieno(3,2-c)pyridine-2(4h)-enye ihydrochloride

Inkcazelo emfutshane:

CAS no: 115473-15-9

Iimpawu zeMichiza: I-Prasugrel Intermediates


Iinkcukacha zeMveliso

Iithegi zeMveliso

Usebenzisa

I-5,6,7,7a-tetrahydrothieno (3,2-c) pyridine-2 (4h) -enye i-hydrochloride isetyenziswa njengendawo ephakathi yePrasugrel.
I-Prasugrel yi-thiophenopyridine antiplatelet eyenziwe ngu-Eli Lilly kunye ne-daiichisankyo, umenzi weyeza waseJapan.Lichiza elandulelayo.Yenza i-molecule esebenzayo emva kwe-metabolism ngokusebenzisa i-cytochrome P450 esibindi kwaye idibanisa ne-platelet P2Y12 receptor ukwenza i-active against platelet aggregation.Izifundo zeklinikhi zibonakalise ukuba i-60 mg yedosi inefuthe elingcono le-anticoagulant kune-300 mg yedosi eqhelekileyo kunye ne-600 mg yonyuso lwedosi ye-clopidogrel, enokunciphisa umngcipheko obanzi wokuhlaselwa sisifo sentliziyo, ukubetha kunye nokufa ngenxa yesifo sentliziyo ngama-20%, kwaye inesiphumo esikhawulezayo. , isiphumo esihle sokunyanga, ukunganyangeki kakuhle kweziyobisi kunye ne-bioavailability, kunye netyhefu ephantsi.

Uluhlu lweeMveliso ezidityanisiweyo

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Isatifikethi

JIN DUN Medical uyeIsiqinisekiso se-ISO kwaye sidibana nemigangatho yemveliso ye-GMP, kuqeshwe iingcali zasekhaya nezangaphandle zokwenziwa kweziyobisi ezinamava atyebileyo ukukhokela iR&D yenkampani.

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Izinto eziluncedo kwiMedical Customization

I-TECHNOL OGY I-ADVANTAGES
●Uxinzelelo oluPhezulu lweCatalytic Hydrogenation.Uxinzelelo oluPhezulu lwe-Hydrogenolysis Reaction.I-Cryogenic Reaction (<-78%C)
● I-Aromatic Heterocyclic Synthesis
● Ukusabela ngokutsha
● IsiGqibo seChiral
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction

I-JIN DUN R&D

Izixhobo

ILebhu yethu inezixhobo ezahlukeneyo zovavanyo kunye novavanyo, ezifana ne: NMR (Bruker 400M) ,HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, iKhalorimitha yokuSkena okwahlukileyo (DSC), iMicroscope ye-Electron...

R&D Iqela

I-Jindun Medical ineqela labasebenzi abaqeqeshiweyo be-R&D, kwaye iqeshe iingcali ezininzi zokwenziwa kweziyobisi zasekhaya nezangaphandle ukukhokela i-R&D, ukwenza udibaniso lwethu luchaneke ngakumbi kwaye lusebenze kakuhle.

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Ukwabelana ngetyala

Siye sanceda iinkampani ezininzi eziphezulu zamachiza zasekhaya, ezifanaHansoh, Hengrui kunye ne-HEC Pharm.Apha siza kubonisa inxalenye yazo.

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Customization Case One:

Inombolo yeCas: 110351-94-5

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Ityala leSibini:

Inombolo yeCas: 144848-24-8

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Customization Case Three:

Inombolo yeCas: 200636-54-0

Imo yeNtsebenziswano

1.Lungiselela abaPhakathi abatsha okanye ii-APIs.Ngokufanayo nokwabelana ngetyala elingasentla, abathengi baneemfuno ze-Intermediates ezithile okanye ii-APIs, kwaye abanakuzifumana iimveliso ezifunekayo kwimarike, ngoko sinokunceda ukwenza ngokwezifiso.

2.Ukuphuculwa kweNkqubo yeeMveliso eziDala.Iqela lethu liya kunceda ukukhulisa nokuphucula imveliso enjalo indlela yokusabela indala, ixabiso lemveliso liphezulu, kwaye ukusebenza kakuhle kuphantsi.Sinokubonelela ngamaxwebhu apheleleyo okuhanjiswa kwetekhnoloji kunye nokuphuculwa kwenkqubo, sincede umthengi kwimveliso esebenzayo.

Ukusuka ekujoliswe kuko ngamachiza ukuya kwi-INDs, iJIN DUN Medical ikubonelelaisitophu esinye sezisombululo ze-R&D ezenzelwe wena.

I-JIN DUN Medical igxininisa ekudaleni iqela elinamaphupha, ukwenza iimveliso ezinesidima, ubuqili, ubukhali, kwaye uphume konke ukuze ube liqabane elithembekileyo kunye nomhlobo wabathengi!


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