Hydroxypyrazolodpyrimidine pyrazolo(3,4-d)pyrimidin-1-ol
Hydroxypyrazolodpyrimidine pyrazolo(3,4-d)pyrimidin-1-ol
Isetyenziswa ngokweklinikhi kwi-hyperuricemia ephambili kunye neyesibini, ngakumbi kwizigulane ezine-hyperuricemia, kunye nezigulane ezinokungaphumeleli kwezintso, kunye nezigulane ezine-gout ephindaphindiweyo okanye engapheliyo, kunye nezigulane ezine-Hyperuricemia.Isetyenziswe kwizigulane ezine-Gouty nephropathy ukukhulula iimpawu kunye nokunciphisa ukubunjwa kwamatye e-uric acid ezintso;amatye e-gout;isetyenziswa kwi-uric acid kwizintso zamatye kunye nesifo sezintso ze-uric acid.
Le mveliso kunye ne-metabolites yayo inokunqanda i-xanthine oxidase, ukuze i-hypoxanthine kunye ne-xanthine ingaguqulwa ibe yi-uric acid, oko kukuthi, ukuhlanganiswa kwe-uric acid kuyancipha, ngaloo ndlela kuncitshiswe ukuxinwa kwe-uric acid egazini kunye nokunciphisa ukuxinwa kwe-uric acid. amathambo, Amalungu kunye nezintso, amachiza anokuthintela ukwakheka kweuric acid.Le mveliso inokuthintela umsebenzi we-enzyme yeziyobisi zesibindi.
(1) .I-hyperuricemia ephambili kunye neyesibini, ngakumbi abo banemveliso ye-uric acid egqithisileyo, nayo isetyenziselwa i-hyperuricemia kunye nokungasebenzi kakuhle kwezintso;
(2) .Ukunyangwa kwe-gout, efanelekileyo kwi-gout ephindaphindiweyo okanye engapheliyo.Kwizigulane ezine-gouty nephropathy, inokunciphisa iimpawu kunye nokunciphisa ukubunjwa kwamatye e-uric acid kwizintso;
(3) .uTophi;
(4) .Isetyenziselwa amatye ezintso ze-uric acid kunye (okanye) uric acid nephropathy.
Umgangatho:usp42
Isivavanyi:98-102%
Umphandle:Umgubo omhlophe okanye phantse omhlophe
Umqulu :25kg/ibhegi
Kukho ukunyanzeliswa kwamathambo, okunokubangela i-pancytopenia, kwaye ichiza kufuneka lipheliswe ukuba kuyimfuneko.Sela amanzi amaninzi ngexesha lonyango, kwaye wenze umchamo ungathathi hlangothi okanye i-alkaline ukukhupha i-diuretic acid.Le mveliso kufuneka isetyenziswe emva kokuba ukuvuvukala okukhulu kwe-gouty arthritis kunyamalale (ngokuqhelekileyo malunga neeveki ezimbini emva kokuqala).Ngexesha lonyango, umfanekiso wegazi kunye nesibindi kunye nokusebenza kwezintso kufuneka kuhlolwe rhoqo.
JIN DUN Medical uyeIsiqinisekiso se-ISO kwaye sidibana nemigangatho yemveliso ye-GMP, kuqeshwe iingcali zasekhaya nezangaphandle zokwenziwa kweziyobisi ezinamava atyebileyo ukukhokela iR&D yenkampani.
I-TECHNOL OGY I-ADVANTAGES
●Uxinzelelo oluPhezulu lweCatalytic Hydrogenation.Uxinzelelo oluPhezulu lwe-Hydrogenolysis Reaction.I-Cryogenic Reaction (<-78%C)
● I-Aromatic Heterocyclic Synthesis
● Ukusabela ngokutsha
● IsiGqibo seChiral
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction
Izixhobo
ILebhu yethu inezixhobo ezahlukeneyo zovavanyo kunye novavanyo, ezifana ne: NMR (Bruker 400M) ,HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, iKhalorimitha yokuSkena okwahlukileyo (DSC), iMicroscope ye-Electron...
R&D Iqela
I-Jindun Medical ineqela labasebenzi abaqeqeshiweyo be-R&D, kwaye iqeshe iingcali ezininzi zokwenziwa kweziyobisi zasekhaya nezangaphandle ukukhokela i-R&D, ukwenza udibaniso lwethu luchaneke ngakumbi kwaye lusebenze kakuhle.
Siye sanceda iinkampani ezininzi eziphezulu zamachiza zasekhaya, ezifanaHansoh, Hengrui kunye ne-HEC Pharm.Apha siza kubonisa inxalenye yazo.
Customization Case One:
Inombolo yeCas: 110351-94-5
Ityala leSibini:
Inombolo yeCas: 144848-24-8
Customization Case Three:
Inombolo yeCas: 200636-54-0
1.Lungiselela abaPhakathi abatsha okanye ii-APIs.Ngokufanayo nokwabelana ngetyala elingasentla, abathengi baneemfuno ze-Intermediates ezithile okanye ii-APIs, kwaye abanakuzifumana iimveliso ezifunekayo kwimarike, ngoko sinokunceda ukwenza ngokwezifiso.
2.Ukuphuculwa kweNkqubo yeeMveliso eziDala.Iqela lethu liya kunceda ukukhulisa nokuphucula imveliso enjalo indlela yokusabela indala, ixabiso lemveliso liphezulu, kwaye ukusebenza kakuhle kuphantsi.Sinokubonelela ngamaxwebhu apheleleyo okuhanjiswa kwetekhnoloji kunye nokuphuculwa kwenkqubo, sincede umthengi kwimveliso esebenzayo.
Ukusuka ekujoliswe kuko ngamachiza ukuya kwi-INDs, iJIN DUN Medical ikubonelelaisitophu esinye sezisombululo ze-R&D ezenzelwe wena.
I-JIN DUN Medical igxininisa ekudaleni iqela elinamaphupha, ukwenza iimveliso ezinesidima, ubuqili, ubukhali, kwaye uphume konke ukuze ube liqabane elithembekileyo kunye nomhlobo wabathengi!
![1,4′-Bipiperidine]-1′-carbonyl chloride HCl](http://cdn.globalso.com/jindunchem-med/image211-300x300.png)
