I-Ethylmethyl-carbamic chloride
I-Ethylmethyl-carbamic chloride
I-Ethylmethyl-carbamic chloride isetyenziswa njengendawo ephakathi ye-Rivastigmine tartrate.
I-rivastigmine tartrate yi-rivastigmine i-Alzheimer's disease drug, i-rivastigmine yi-physostigmine derivative yi-Novartis okokuqala iphuhliswe ngempumelelo igama lorhwebo i-Exelon (exelon), i-molecule enesakhiwo se-carbamate, luhlobo lwe-amino acid ye-cerebral cholinesterase inhibitor ekhethiweyo, inokunqanda. i-acetylcholinesterase kunye ne-butyrylcholinesterase, i-cholinergic neurons ngokulibazisa ukukhululwa kwe-acetylcholine degradation kunye namandla okukhuthaza i-cholinergic nerve conduction, inokuphucula ukuphazamiseka komsebenzi wokuqonda okuxutyushwa yi-cholinergic, ngaloo ndlela iphucula umsebenzi wokuqonda wezigulane ze-Alzheimer's disease.I-Rivastigmine i-protein ye-plasma yokubopha ibuthathaka, ngokulula ngokusebenzisa umqobo wegazi-ingqondo, enezinga eliphezulu lokukhetha kwengqondo.Ayisebenzi nje ngokukhethayo kweyona cortex yecerebral echaphazeleka lula kunye nehippocampus, kodwa ikwanqanda ngokukhethekileyo uhlobo olusezantsi lwe-AChE ebuchosheni, okukhokelela ekunciphiseni ukusebenza kweziphumo ebezingalindelekanga ze-peripheral cholinergic.I-Rivastigmine kwi-vivo-half-life ifutshane kunye nexesha elide lesenzo.Ngokungafaniyo ne-tacrine, le mveliso kwi-hippocampus kunye ne-cortex ye-G1 enzyme inhibitory effect yomelele.Ikliniki yonyango lwesifo sengqondo esixhalabisayo esiphakathi ukuya kwesasiphakathi se-Alzheimer, okanye isifo sika-Alzheimer sinokukrokrelwa ukuba sisifo sika-Alzheimer ngokwezonyango.
JIN DUN Medical uyeIsiqinisekiso se-ISO kwaye sidibana nemigangatho yemveliso ye-GMP, kuqeshwe iingcali zasekhaya nezangaphandle zokwenziwa kweziyobisi ezinamava atyebileyo ukukhokela iR&D yenkampani.
I-TECHNOL OGY I-ADVANTAGES
●Uxinzelelo oluPhezulu lweCatalytic Hydrogenation.Uxinzelelo oluPhezulu lwe-Hydrogenolysis Reaction.I-Cryogenic Reaction (<-78%C)
● I-Aromatic Heterocyclic Synthesis
● Ukusabela ngokutsha
● IsiGqibo seChiral
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction
Izixhobo
ILebhu yethu inezixhobo ezahlukeneyo zovavanyo kunye novavanyo, ezifana ne: NMR (Bruker 400M) ,HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, iKhalorimitha yokuSkena okwahlukileyo (DSC), iMicroscope ye-Electron...
R&D Iqela
I-Jindun Medical ineqela labasebenzi abaqeqeshiweyo be-R&D, kwaye iqeshe iingcali ezininzi zokwenziwa kweziyobisi zasekhaya nezangaphandle ukukhokela i-R&D, ukwenza udibaniso lwethu luchaneke ngakumbi kwaye lusebenze kakuhle.
Siye sanceda iinkampani ezininzi eziphezulu zamachiza zasekhaya, ezifanaHansoh, Hengrui kunye ne-HEC Pharm.Apha siza kubonisa inxalenye yazo.
Customization Case One:
Inombolo yeCas: 110351-94-5
Ityala leSibini:
Inombolo yeCas: 144848-24-8
Customization Case Three:
Inombolo yeCas: 200636-54-0
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2.Ukuphuculwa kweNkqubo yeeMveliso eziDala.Iqela lethu liya kunceda ukukhulisa nokuphucula imveliso enjalo indlela yokusabela indala, ixabiso lemveliso liphezulu, kwaye ukusebenza kakuhle kuphantsi.Sinokubonelela ngamaxwebhu apheleleyo okuhanjiswa kwetekhnoloji kunye nokuphuculwa kwenkqubo, sincede umthengi kwimveliso esebenzayo.
Ukusuka ekujoliswe kuko ngamachiza ukuya kwi-INDs, iJIN DUN Medical ikubonelelaisitophu esinye sezisombululo ze-R&D ezenzelwe wena.
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