2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile

I-2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile isetyenziswa njengendawo ephakathi ye-Trelagliptin succinate.

I-Trogliptin succinate sisithinteli se dipeptidyl peptidase Ⅳ (DPP - Ⅳ) ephuhliswe yi-Takeda (Takeda Pharmaceutical Co., Ltd.) eJapan.Inokuthintela ngokukhethayo nangokuqhubekayo iDPP - Ⅳ kwaye ilawule izinga leswekile yegazi.Ulingo lwezonyango lubonisa ukuba ichiza linokhuseleko olululo kunye nokusebenza kakuhle.Kanye ngeveki inokulawula ngokufanelekileyo inqanaba le-glucose yegazi kunye nokuphucula ukuthotyelwa kweyeza kwizigulane.NgoMeyi, 2015, ichiza lamkelwa yi-PMDA yaseJapan ukuba lidweliswe kunyango lwesifo seswekile.