I-6-tetra-O-acteyl-1-C-[4-chloro-3-[[4-[(3S)-tetrahydrofu-ran-3-yl]oxy]phenyl]

Le mveliso icwecwe elikhanyayo elityheli eligqunywe ngefilimu, limhlophe okanye liphantse libe mhlophe emva kokususa ingubo.

Iimpawu
Le mveliso ifanelekile kunyango lwe-2 yeswekile.

I-Monotherapy
Le mveliso isetyenziselwa kunye nokulawulwa kokutya kunye nokuzivocavoca ukuphucula ulawulo lweswekile yegazi kwizigulane ezine-2 yeswekile.

Isetyenziswe ngokudibeneyo ne-metformin hydrochloride
Xa i-metformin hydrochloride yodwa ayikwazi ukulawula ngokufanelekileyo iswekile yegazi, le mveliso ingasetyenziselwa ngokudibanisa ne-metformin hydrochloride ukuphucula ulawulo lweswekile yegazi kwizigulane ezinesifo sikashukela sohlobo lwe-2 ngesiseko sokutya kunye nokuzivocavoca.

Isetyenziswe ngokudibeneyo ne-metformin hydrochloride kunye ne-sulfonylureas.
Xa usetyenziso oludityanisiweyo lwe-metformin hydrochloride kunye ne-sulfonylureas alukwazi ukulawula ngokufanelekileyo iswekile yegazi, le mveliso inokusetyenziswa ngokudibeneyo ne-metformin hydrochloride kunye ne-sulfonylureas ukuphucula ulawulo lweswekile yegazi kwizigulana ezinesifo seswekile se-2 ngesiseko sokutya kunye nokuzilolonga.

Izithintelo zamayeza
Le mveliso ayikhuthazwa kwizigulane ezinesifo seswekile okanye unyango lwe-ketoacidosis yesifo sikashukela.

Inkcazo
(1) 10 mg;(2) 25 mg.

Umthamo
Idosi ecetyiswayo.
Umthamo onconywayo wale mveliso ngu-10 mg ekuseni, kanye ngosuku, kwisisu esingenalutho okanye emva kokutya.Kwizigulane ezinyamezela le mveliso, idosi inokunyuswa ukuya kwi-25 mg (jonga [uvavanyo lweKlinikhi]).
Kwizigulane ezine-hypovolemia, kucetyiswa ukuba kulungiswe i-hypovolemia ngaphambi kokuba uqale ukusebenzisa le mveliso (bona [Iingcebiso]).

Izigulana ezinokukhubazeka kwezintso.
Kucetyiswa ukuba uvavanye umsebenzi wezintso ngaphambi kokuba uqale ukusebenzisa le mveliso, kwaye ke kufuneka ihlolwe rhoqo.
Izigulane ezine-eGFR engaphantsi kwe-45 mL / min / 1.73 m2 akufanele zisebenzise le mveliso.
Izigulane ezine-eGFR eziphezulu okanye ezilingana ne-45 mL / min / 1.73 m2 ayifuni ukulungelelanisa umthamo.
Ukuba i-eGFR iphantsi ngokuqhubekayo kune-45 mL/min/1.73 m2, le mveliso kufuneka iyekwe (bona [Iimiqathango]).

Izigulane ezinomonakalo wesibindi.
Izigulane ezinomonakalo wesibindi azidingi ukulungelelanisa umthamo.Ukuvezwa kwe-Enpagliflozin kwandiswe kwizigulana ezinomonakalo omkhulu wesibindi.Amava onyango lwezigulane ezinomonakalo omkhulu wesibindi zilinganiselwe, ngoko ke, akukhuthazwa kule nxalenye yabemi.