I-1,5-Pentanediol diacrylate

I-1,5-Pentanediol diacrylate isetyenziswe njengendawo ephakathi kweCisatracurium besylate.
I-Cisatracurium besylate luhlobo lwetyuwa lwe-benzene sulfonate lwe-atracurium.Luhlobo lwe-artificially synthetic non-depolarizing izihlunu zokuphumza kunye nendima yayo efana ne-tubocurarine.Inexesha lokuqala lomzuzu we-1 kunye nexesha elide le-15 imizuzu.Umthamo wonyango awuchaphazeli intliziyo, isibindi kunye nomsebenzi wezintso.Kananjalo ayinayo ipropati yokuqokelela.Isenokwenza ukuba kukhutshwe i-histamine xa isetyenziswa kumthamo omkhulu.Ukuphumla kwe-muscle okanye ukulawulwa kokuphefumula okufunekayo kuqhaqho, xa kuthelekiswa neyeza zangoku zeklinikhi ezinkulu ze-muscle-relaxing anesthetic, i-cisatracurium besylate ayinayo i-metabolized ngesibindi okanye izintso, kwaye ine-cardiovascular stability;umphumo walo wokuphumla kwemisipha ngamaxesha e-3 anamandla njenge-atracurium ngaphandle kwemiphumo emibi ye-cardiovascular.I-Cisatracurium besylate isetyenziswa kakhulu kwi-anesthesia jikelele, kwaye ingasetyenziselwa ngokubanzi kwi-intubation, ukuphatha isibindi kunye nokungasebenzi kakuhle kwezintso, ezisetyenziselwa utyando lwe-cardiovascular and asebekhulile kunye nezigulane zabantwana.
Xa kuthelekiswa ne-atracurium, le mveliso ayinayo imiphumo emibi exhomekeke kumthamo wokukhutshwa kwe-histamine;nangona kunjalo, into engalunganga kukuba izigulane ezinesifo sesibindi kunye nezintso kufuneka zilawule ngokuqaphela.
Ukusukela ngo-1996 okokuqala ngqa xa eli chiza lingena kwimarike e-UK, amazwe angaphandle aye alisebenzisa ngokuthe ngcembe ukuba athathe indawo ye-vecuronium kunye ne-atracurium njengeyona ndlela iphambili yokuphumza izihlunu.