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Ukubonelela nge-ODM 5-(2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl)-4, 5, 6, 7-Tetrahydrothieno[3, 2-C]Pyridin-2-Yl Acetate Hydrochloride

Ukubonelela nge-ODM 5-(2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl)-4, 5, 6, 7-Tetrahydrothieno[3, 2-C]Pyridin-2-Yl Acetate Hydrochloride

Inkcazelo emfutshane:

CAS no: 115473-15-9

Iimpawu zeMichiza: I-Prasugrel Intermediates


Iinkcukacha zeMveliso

Iithegi zeMveliso

Amava olawulo lweeprojekthi ezityebileyo ngendlela engakholelekiyo kunye nomntu kwimodeli yenkonzo ye-1 yenza ukubaluleka konxibelelwano lwentlangano kunye nokuqonda kwethu ngokulula okulindelekileyo kwi-Supply ODM 5-(2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl)- 4, 5, 6, 7-Tetrahydrothieno [3, 2-C] Pyridin-2-Yl Acetate Hydrochloride, inzuzo yabaThengi kunye nokwaneliseka ngokuqhelekileyo kujoliswe kuyo enkulu.Qiniseka ukuba usitsalele umnxeba.Sinike ithuba, sikunikeze umothuko.
Amava olawulo lweeprojekthi ezityebileyo ngendlela emangalisayo kunye nomntu kwimodeli yenkonzo e-1 yenza ukubaluleka konxibelelwano lombutho kunye nokuqonda kwethu ngokulula okulindelekileyoChina CAS NO NO: 389574-19-0, Wamkelekile ukuba undwendwele inkampani yethu, umzi-mveliso kunye nendawo yethu yokubonisa apho ibonisa iimveliso ezahlukeneyo zeenwele eziza kuhlangabezana nolindelo lwakho.Okwangoku, kulungele ukutyelela iwebhusayithi yethu, kwaye abasebenzi bethu beentengiso baya kuzama konke okusemandleni abo ukukuzisa eyona nkonzo ilungileyo.Kufuneka uqhagamshelane nathi ukuba ufuna ulwazi oluthe kratya.Injongo yethu kukunceda abathengi baqonde iinjongo zabo.Besisenza iinzame ezinkulu ukuphumeza le meko yokuphumelela.

I-5,6,7,7a-tetrahydrothieno (3,2-c) pyridine-2 (4h) -enye i-hydrochloride isetyenziswa njengendawo ephakathi yePrasugrel.
I-Prasugrel yi-thiophenopyridine antiplatelet eyenziwe ngu-Eli Lilly kunye ne-daiichisankyo, umenzi weyeza waseJapan.Lichiza elandulelayo.Yenza i-molecule esebenzayo emva kwe-metabolism ngokusebenzisa i-cytochrome P450 esibindi kwaye idibanisa ne-platelet P2Y12 receptor ukwenza i-active against platelet aggregation.Izifundo zeklinikhi zibonakalise ukuba i-60 mg yedosi inefuthe elingcono le-anticoagulant kune-300 mg yedosi eqhelekileyo kunye ne-600 mg yonyuso lwedosi ye-clopidogrel, enokunciphisa umngcipheko obanzi wokuhlaselwa sisifo sentliziyo, ukubetha kunye nokufa ngenxa yesifo sentliziyo ngama-20%, kwaye inesiphumo esikhawulezayo. , isiphumo esihle sokunyanga, ukunganyangeki kakuhle kweziyobisi kunye ne-bioavailability, kunye netyhefu ephantsi.

Amava olawulo lweeprojekthi ezityebileyo ngendlela engakholelekiyo kunye nomntu kwimodeli yenkonzo ye-1 yenza ukubaluleka konxibelelwano lwentlangano kunye nokuqonda kwethu ngokulula okulindelekileyo kwi-Supply ODM 5-(2-Cyclopropyl-1-(2-Fluorophenyl)-2-Oxoethyl)- 4, 5, 6, 7-Tetrahydrothieno [3, 2-C] Pyridin-2-Yl Acetate Hydrochloride, inzuzo yabaThengi kunye nokwaneliseka ngokuqhelekileyo kujoliswe kuyo enkulu.Qiniseka ukuba usitsalele umnxeba.Sinike ithuba, sikunikeze umothuko.
Ukubonelela nge-ODMChina CAS NO NO: 389574-19-0, Wamkelekile ukuba undwendwele inkampani yethu, umzi-mveliso kunye nendawo yethu yokubonisa apho ibonisa iimveliso ezahlukeneyo zeenwele eziza kuhlangabezana nolindelo lwakho.Okwangoku, kulungele ukutyelela iwebhusayithi yethu, kwaye abasebenzi bethu beentengiso baya kuzama konke okusemandleni abo ukukuzisa eyona nkonzo ilungileyo.Kufuneka uqhagamshelane nathi ukuba ufuna ulwazi oluthe kratya.Injongo yethu kukunceda abathengi baqonde iinjongo zabo.Besisenza iinzame ezinkulu ukuphumeza le meko yokuphumelela.


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