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Iingcaphuno zeEthylmethyl-Carbamic Chloride;N-Ethyl-N-Methylcarbamoyl Chloride

Iingcaphuno zeEthylmethyl-Carbamic Chloride;N-Ethyl-N-Methylcarbamoyl Chloride

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CAS no: 42252-34-6

Iimpawu zeMichiza: I-Rivastigmine tartrate Intermediates


Iinkcukacha zeMveliso

Iithegi zeMveliso

Thatha umsebenzi opheleleyo wokwanelisa zonke iimfuno zabathengi bethu;ukufumana inkqubela phambili eqhubekayo ngokukhuthaza ukuqhubela phambili kwabathengi bethu;khula ube liqabane lokugqibela lentsebenziswano yabathengi kunye nokwandisa umdla wabathengi beQuots ye-Ethylmethyl-Carbamic Chloride;N-Ethyl-N-Methylcarbamoyl Chloride, Besifuna phambili ukuseka imibutho yentsebenziswano kunye nawe.Qinisekisa ukuba uqhagamshelane nathi ngedatha engaphezulu.
Thatha umsebenzi opheleleyo wokwanelisa zonke iimfuno zabathengi bethu;ukufumana inkqubela phambili eqhubekayo ngokukhuthaza ukuqhubela phambili kwabathengi bethu;khula ube liqabane lokugqibela lentsebenziswano yabathengi kwaye wandise umdla wabathengiChina Ethylmethyl-Carbamic Chloride;N-Ethyl-N-, Sibe liqabane lakho elithembekileyo kwiimarike zamazwe ngamazwe zezinto zethu.Sigxila ekuboneleleni ngenkonzo kubaxumi bethu njengento ephambili ekomelezeni ubudlelwane bethu bexesha elide.Ubukho obuqhubekayo beemveliso zodidi oluphezulu zidityaniswe nenkonzo yethu ebalaseleyo yaphambi nasemva kokuthengisa kuqinisekisa ukhuphiswano olomeleleyo kwimakethi ekhulayo yehlabathi.Sizimisele ukusebenzisana nabahlobo bezoshishino basekhaya nakwamanye amazwe, ukudala ikamva elihle.Wamkelekile kuNdwendwela umzi-mveliso wethu.Ndijonge phambili ukuba nentsebenziswano win-win nawe.

I-Ethylmethyl-carbamic chloride isetyenziswa njengendawo ephakathi ye-Rivastigmine tartrate.
I-rivastigmine tartrate yi-rivastigmine i-Alzheimer's disease drug, i-rivastigmine yi-physostigmine derivative yi-Novartis okokuqala iphuhliswe ngempumelelo igama lorhwebo i-Exelon (exelon), i-molecule enesakhiwo se-carbamate, luhlobo lwe-amino acid ye-cerebral cholinesterase inhibitor ekhethiweyo, inokunqanda. i-acetylcholinesterase kunye ne-butyrylcholinesterase, i-cholinergic neurons ngokulibazisa ukukhululwa kwe-acetylcholine degradation kunye namandla okukhuthaza i-cholinergic nerve conduction, inokuphucula ukuphazamiseka komsebenzi wokuqonda okuxutyushwa yi-cholinergic, ngaloo ndlela iphucula umsebenzi wokuqonda wezigulane ze-Alzheimer's disease.I-Rivastigmine i-protein ye-plasma yokubopha ibuthathaka, ngokulula ngokusebenzisa umqobo wegazi-ingqondo, enezinga eliphezulu lokukhetha kwengqondo.Ayisebenzi nje ngokukhethayo kweyona cortex yecerebral echaphazeleka lula kunye nehippocampus, kodwa ikwanqanda ngokukhethekileyo uhlobo olusezantsi lwe-AChE ebuchosheni, okukhokelela ekunciphiseni ukusebenza kweziphumo ebezingalindelekanga ze-peripheral cholinergic.I-Rivastigmine kwi-vivo-half-life ifutshane kunye nexesha elide lesenzo.Ngokungafaniyo ne-tacrine, le mveliso kwi-hippocampus kunye ne-cortex ye-G1 enzyme inhibitory effect yomelele.Ikliniki yonyango lwesifo sengqondo esixhalabisayo esiphakathi ukuya kwesasiphakathi se-Alzheimer, okanye isifo sika-Alzheimer sinokukrokrelwa ukuba sisifo sika-Alzheimer ngokwezonyango.

Thatha umsebenzi opheleleyo wokwanelisa zonke iimfuno zabathengi bethu;ukufumana inkqubela phambili eqhubekayo ngokukhuthaza ukuqhubela phambili kwabathengi bethu;khula ube liqabane lokugqibela lentsebenziswano yabathengi kunye nokwandisa umdla wabathengi beQuots ye-Ethylmethyl-Carbamic Chloride;N-Ethyl-N-Methylcarbamoyl Chloride, Besifuna phambili ukuseka imibutho yentsebenziswano kunye nawe.Qinisekisa ukuba uqhagamshelane nathi ngedatha engaphezulu.
Iingcaphuno zeChina Ethylmethyl-Carbamic Chloride;N-Ethyl-N-, Sibe liqabane lakho elithembekileyo kwiimarike zamazwe ngamazwe zezinto zethu.Sigxila ekuboneleleni ngenkonzo kubaxumi bethu njengento ephambili ekomelezeni ubudlelwane bethu bexesha elide.Ubukho obuqhubekayo beemveliso zodidi oluphezulu zidityaniswe nenkonzo yethu ebalaseleyo yaphambi nasemva kokuthengisa kuqinisekisa ukhuphiswano olomeleleyo kwimakethi ekhulayo yehlabathi.Sizimisele ukusebenzisana nabahlobo bezoshishino basekhaya nakwamanye amazwe, ukudala ikamva elihle.Wamkelekile kuNdwendwela umzi-mveliso wethu.Ndijonge phambili ukuba nentsebenziswano win-win nawe.


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