Isaphulelo Esiqhelekileyo esiPhakathi CAS.288573-56-8 1- (tert-Butoxycarbonyl) -4-[ (4-fluorophenyl) Amino]Piperidine

Sixhomekeke ekucingeni okucwangcisiweyo, ukuphuculwa okuthe gqolo kuwo onke amacandelo, inkqubela phambili yetekhnoloji kwaye kunjalo nakubasebenzi bethu abathatha inxaxheba ngokuthe ngqo kwimpumelelo yethu kwi-CAS yesaphulelo esiQhelekileyo esiPhakathi.288573-56-8 1- (tert-Butoxycarbonyl) -4-[ (4-fluorophenyl) Amino]Piperidine, Izinto ziphumelele izatifikethi ngelixa kusetyenziswa amagunya aphambili ommandla kunye namazwe ngamazwe.Ngolwazi oluthe vetshe ngakumbi, nceda uqhagamshelane nathi!
Sixhomekeke ekucingeni okucwangcisiweyo, uhlengahlengiso oluqhubekayo kuwo onke amacandelo, inkqubela phambili yetekhnoloji kwaye kunjalo nakubasebenzi bethu abathatha inxaxheba ngokuthe ngqo kwimpumelelo yethuChina [(4-fluorophenyl)amino] kunye nefluorophenyl) Amino]Piperidine, Sikwinkonzo eqhubekayo kubathengi bethu abakhulayo basekhaya nabamazwe ngamazwe.Sijonge ukuba yinkokeli yehlabathi jikelele kolu shishino nangale ngqondo;kuluvuyo lwethu ukukhonza kunye nokuzisa awona mazinga aphezulu okwaneliseka phakathi kwemarike ekhulayo.

I-2-bromo-2- (2-fluorophenyl) -1-cyclopropylethanone isetyenziswe njengendawo ephakathi yePrasugrel.
I-Prasugrel yi-thiophenopyridine antiplatelet eyenziwe ngu-Eli Lilly kunye ne-daiichisankyo, umenzi weyeza waseJapan.Lichiza elandulelayo.Yenza i-molecule esebenzayo emva kwe-metabolism ngokusebenzisa i-cytochrome P450 esibindi kwaye idibanisa ne-platelet P2Y12 receptor ukwenza i-active against platelet aggregation.Izifundo zeklinikhi zibonakalise ukuba i-60 mg yedosi inefuthe elingcono le-anticoagulant kune-300 mg yedosi eqhelekileyo kunye ne-600 mg yonyuso lwedosi ye-clopidogrel, enokunciphisa umngcipheko obanzi wokuhlaselwa sisifo sentliziyo, ukubetha kunye nokufa ngenxa yesifo sentliziyo ngama-20%, kwaye inesiphumo esikhawulezayo. , isiphumo esihle sokunyanga, ukunganyangeki kakuhle kweziyobisi kunye ne-bioavailability, kunye netyhefu ephantsi.

Sixhomekeke ekucingeni okucwangcisiweyo, ukuphuculwa okuthe gqolo kuwo onke amacandelo, inkqubela phambili yetekhnoloji kwaye kunjalo nakubasebenzi bethu abathatha inxaxheba ngokuthe ngqo kwimpumelelo yethu kwi-CAS yesaphulelo esiQhelekileyo esiPhakathi.288573-56-8 1- (tert-Butoxycarbonyl) -4-[ (4-fluorophenyl) Amino]Piperidine, Izinto ziphumelele izatifikethi ngelixa kusetyenziswa amagunya aphambili ommandla kunye namazwe ngamazwe.Ngolwazi oluthe vetshe ngakumbi, nceda uqhagamshelane nathi!
Isaphulelo EsiqhelekileyoChina [(4-fluorophenyl)amino] kunye nefluorophenyl) Amino]Piperidine, Sikwinkonzo eqhubekayo kubathengi bethu abakhulayo basekhaya nabamazwe ngamazwe.Sijonge ukuba yinkokeli yehlabathi jikelele kolu shishino nangale ngqondo;kuluvuyo lwethu ukukhonza kunye nokuzisa awona mazinga aphezulu okwaneliseka phakathi kwemarike ekhulayo.