Izinga leziganeko zomhlaza wedlala lesidoda liya likhula unyaka nonyaka, kwaye liye laba ngomnye wababulali abakhulu abachaphazela impilo yamadoda asele ekhulile.Okwangoku, i-China iseke imigangatho ecacileyo yokuhlola umhlaza we-prostate, kodwa kusafuneka iqhubeke nokukhuthaza ukuthandwa kolwazi lovavanyo loluntu.U-Ye Dingwei, usekela mongameli weSibhedlele soMhlaza esidityaniswe neYunivesithi yaseFudan kunye nentloko yesebe le-urology, uthe kwinkomfa yamva nje yenkqubela phambili yomhlaza wesifo somhlaza wedlala lobudoda ebibanjelwe e-Guangzhou ukuba i-China isafuna ukomeleza indima yayo ephambili kuphando lweziyobisi lwamazwe ngamazwe. uphuhliso lwamalingo onyango, ukuze kukhawuleziswe ukwanda kunye nokwaziswa kwamachiza avelisa izinto ezintsha kwaye kuxhamle izigulane ezininzi eTshayina.
Umhlaza wedlala lobudoda yithumba eliyingozi le-epithelial elenzeka kwi-prostate kwaye lelona thumba libi kakhulu kwinkqubo ye-urogenital yamadoda.Ngenxa yokuba ingenazo iimpawu ezithile zeklinikhi kwisigaba sokuqala, ihlala iphosakele ngoogqirha okanye izigulane ngenxa ye-prostatic hypertrophy okanye i-hyperplasia, kwaye izigulane ezininzi azifiki kugqirha de zibe neempawu ze-metastatic ezifana neentlungu zamathambo.Ngenxa yoko, phantse i-70% yezigulana zomhlaza wedlala lobudoda e-China zihambele phambili kwaye zinomhlaza we-prostate obanzi xa ufunyaniswe, ngonyango olulambathayo kunye noxilongo.Ngaphezu koko, izinga lezehlo zomhlaza we-prostate likhula ngokukhula, likhuphuka ngokukhawuleza emva kweminyaka engama-50, kwaye izinga lokufa kunye nezinga lokufa kwe-85 yeminyaka ubudala lifikelela kwincopho.Ngaphantsi kwemvelaphi yokuguga okunzulu e-China, inani elipheleleyo labantu abanomhlaza we-prostate e-China liya kunyuka.
UYe Dingwei uthe izinga lokunyuka kwenqanaba lezehlo zomhlaza wedlala lobudoda e-China ligqithile kwelo lamanye amathumba aqinileyo, kwaye izinga lokufa linyuka kakhulu.Kwangaxeshanye, izinga leminyaka emihlanu lokusinda komhlaza wedlala lobudoda eTshayina lingaphantsi kwama-70%, ngelixa eYurophu naseUnited States, ngakumbi eUnited States, izinga lokusinda leminyaka emihlanu lisondele kwi-100%.“Esona sizathu siphambili sale meko kukuba ulwazi lokuhlolwa kwelizwe lonke eTshayina lusebuthathaka, kwaye akukho mvisiswano malunga nokwazisa ukuba amaqela asemngciphekweni omkhulu kufuneka enze uvavanyo lwePSA rhoqo emva kweminyaka emibini;kwaye ezinye izigulana azikhange zifumane ukuxilongwa ngokusemgangathweni kunye nonyango, kwaye yonke inkqubo yolawulo lomhlaza wedlala lesinyi eTshayina isafuna ukuphuculwa. "
Njengoninzi lomhlaza, ukufunyanwa kwangoko, ukuxilongwa kunye nokunyangwa komhlaza wedlala lesinyi kunokunyusa izinga lokusinda.UZeng Hao, ilungu leQela loPhando loLutsha kunye noNobhala-Jikelele weSebe le-Urology yoMbutho wezoNyango waseTshayina, uthe abantu baseYurophu nabaseMelika babaluleke kakhulu kuthintelo kunye nonyango lomhlaza wedlala lesidoda, kwaye izinga lokujongwa komhlaza wedlala lobudoda lilinganiselwe. ephezulu, evumela izigulane ezininzi ezinomhlaza wedlala lobudoda kwangoko ukuba zifumane amathuba onyango alungileyo, ngelixa uluntu lwaseTshayina lunolwazi oluphantsi lokuhlolwa kwezifo, kwaye uninzi lwezigulana luhambele phambili ekuhlaleni kunye nomhlaza wedlala lobudoda olubanzi xa lufunyenwe.
“Kusekho umsantsa omkhulu phakathi kwabaguli baseTshayina abanomhlaza wedlala lobudoda kunye neYurophu kunye ne-United States ukusuka ekuqaleni ukuya kuxilongo ukuya kunyango ukuya kuxilongo.Ke ngoko, uthintelo kunye nonyango lomhlaza wedlala lobudoda eTshayina lusenendlela ende ekufuneka ihambe,” utshilo uZeng Hao.
Uyitshintsha njani imeko ekhoyo?UYe Dingwei uthe eyokuqala kukwazisa abantu ngovavanyo kwangoko.Izigulana zedlala lobudoda ezingaphezulu kweminyaka engama-50 ezisemngciphekweni omkhulu kufuneka zivavanyelwe i-prostate specific antigen (PSA) qho kwiminyaka emibini.Okwesibini, unyango lomhlaza we-prostate kufuneka luhlawule ingqwalasela engakumbi kunyango lokuchaneka kunye nengcamango yenkqubo epheleleyo.Okwesithathu, kunyango, kufuneka sinikele ingqalelo kwi-multidisciplinary treatment (MDT) kwizigulane ezinomdlavuza we-prostate phakathi nezigaba ezisekupheleni.Ngemizamo edibeneyo yezi ndlela zininzi zingentla, izinga lokusinda komhlaza wedlala lesinyi e-China linokuphuculwa kakhulu kwixesha elizayo.
"Kusenendlela ende ekufuneka siyihambile ekuphuculeni izinga lokuxilongwa kwangoko kunye nezinga lokuchaneka lokuchongwa."UZeng Hao uthe obona bunzima ekuphuculeni ukuxilongwa kwangoko kunye nenqanaba lonyango lwakwangoko kukuba kuqheliselo lwezonyango, ixabiso labamakishi bethumba sisalathiso esibalulekileyo sesalathiso, kwaye ukuxilongwa kwethumba kufuneka kudityaniswe nokucinga okanye ukuhlatywa kwe-biopsy ukuze kubanzi. Ukuxilongwa, kodwa iminyaka ephakathi yezigulane zomhlaza wedlala lobudoda iphakathi kweminyaka engama-67 nama-70 ubudala, Olu hlobo lwezigulane ezisele lukhulile lunolwamkelo oluphantsi lwe-puncture biopsy.
Okwangoku, iindlela zonyango eziqhelekileyo zomhlaza we-prostate ziquka utyando, i-radiotherapy, i-chemotherapy kunye nonyango lwe-endocrine, phakathi kwayo unyango lwe-endocrine yeyona ndlela yonyango yomhlaza we-prostate.
U-Ye Dingwei uthe iziphumo ze-ASCO-GU ezisandula ukukhutshwa kulo nyaka zibonise ukuba unyango oludityanisiweyo olwenziwe yi-PARP inhibitor Talazoparib kunye ne enzalutamide lufumene iziphumo ezilungileyo kulingo lwesigaba sesi-III sekliniki, kwaye ixesha lokusinda lilonke liphuculwe kakhulu, iziphumo ezilindelekileyo ngokwentelekiso, ngethemba lokuphucula umgangatho wobomi bubonke bezigulane ezinomhlaza wedlala lobudoda okwaziyo ukumelana ne-metastatic kwixa elizayo.
"Kusekho izikhewu kwiimarike kunye neemfuno zonyango ezingafezekiyo ekusungulweni kwamachiza avelayo kwilizwe lethu."UYe Dingwei uthe unethemba lokukhawulezisa ukuqaliswa kweziyobisi ezintsha, kwaye unethemba lokuba iqela lezonyango laseTshayina linokuthatha inxaxheba kulingo lwezonyango lwamachiza ehlabathi, ligcine inqanaba elifanayo kunye nophando lwangaphandle kunye nophuhliso kunye nentengiso, kunye nokusebenza kunye ukuzisa ngakumbi. ukhetho olutsha lonyango lwezigulane, ukuphucula izinga lokuxilongwa kwangaphambili kunye nokuphila ngokubanzi.
JinDun Medicalinentsebenziswano yexesha elide yophando lwezenzululwazi kunye neteknoloji yokuxhunyelelwa kwiiyunivesithi zaseTshayina.Ngezixhobo zonyango ezityebileyo zikaJiangsu, inobudlelwane bexesha elide kunye neIndiya, iSoutheast Asia, iSouth Korea, iJapan kunye nezinye iimarike.Ikwabonelela ngeenkonzo zentengiso kunye nentengiso kuyo yonke inkqubo ukusuka phakathi ukuya kwimveliso egqityiweyo ye-API.Sebenzisa izibonelelo eziqokelelweyo zeYangshi Chemical kwichemistry fluorine ukubonelela ngeenkonzo ezizodwa zokwenza imichiza kumaqabane.Ukubonelela ngenkqubo yokuveliswa kwezinto ezintsha kunye neenkonzo zophando lokungcola kubathengi abajoliswe kuyo.
I-JinDun Medical igxininisa ekudaleni iqela elinamaphupha, ukwenza iimveliso ngesidima, ubuqili, ubukhali, kwaye uphume wonke ube liqabane elithembekileyo kunye nomhlobo wabathengi! Ababoneleli besisombululo esisodwa, i-R&D elungiselelweyo kunye neenkonzo zemveliso ezilungiselelwe abaphakathi bamayeza kunye nee-APIs, yobuchwepheshaimveliso yamayeza elungiselelweyo(CMO) kunye nababoneleli ngeenkonzo zeR&D kunye nemveliso (CDMO).
Ixesha lokuposa: Mar-20-2023