Inkcazo ephezulu Ubonelelo 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4

Kunikezelwe kulawulo oluluqilima olugqwesileyo kunye nenkampani yabathengi enenkathalo, abasebenzi bethu abanamava abasebenzisana nabo bahlala befumaneka ukuze baxoxe ngeemfuno zakho kwaye benze ulonwabo oluthile lomthengi olupheleleyo lwenkcazo ephezulu Ubonelelo 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, We' ukulungele ukusebenzisana neshishini nabahlobo abalungileyo abavela endlwini yakho naphesheya kweelwandle kwaye wenze ixesha elide elibalaseleyo ngokudibeneyo.
Uzinikele kulawulo oluluqilima olugqwesileyo kunye nenkampani yabathengi enenkathalo, abasebenzi bethu abanamava abanxulumana nabo bahlala befumaneka ukuze baxoxe ngeemfuno zakho kwaye benze ulonwabo oluthile lomthengiChina Imidazole kunye Imz, Rhoqo ngonyaka, uninzi lwabathengi bethu baya kundwendwela inkampani yethu kwaye bafezekise ukuqhubela phambili kweshishini abasebenza nathi.Siyakwamkela ngokunyanisekileyo ukuba usityelele nangaliphi na ixesha kwaye kunye siya kuphumelela kwimpumelelo enkulu kwishishini leenwele.

Iphakathi kwi-synthesis ye-allopurinol.

Ngomnye we-3-amino-4-substituted pyrazole series.Ingasetyenziswa njengendawo ephakathi ukudibanisa iikhompawundi ezininzi ze-pharmacologically ezisebenzayo ze-organic, ezifana ne-allopurinol, enye ye-pyrazolopyrimidine derivatives series, le yokugqibela ukususela ngo-1963 Ukususela ekusetyenzisweni kwayo kwezonyango, iye yaba iyeza eliphambili lokunyanga i-gout.Okwangoku, zimbalwa iindlela ezaziwayo zokudibanisa

I-3-aminopyrazole-4-carboxamide hemisulfate e-China, ngokukodwa ngokuphendula i-malononitrile kunye ne-triethyl orthoformate ukulungiselela i-ethoxymethylene malononitrile, kwaye emva koko kunye ne-Reactivity ye-hydrazine hydrate ivelisa i-3-amino-4-cyanopyrazole, ekugqibeleni isabela nge-asidi egxininisiweyo yokuvelisa i-sulfuric acid.

3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis of 4-formamide hemisulfate [J]. Chemical Industry Times, 2008, 6 (22): 39 40), isivuno siphelele i-synthesis ngale ndlela malunga ne-60% (ibalwa njenge-malononitrile), le ndlela Ibandakanya ukuphendulwa kwamanyathelo amathathu, amanyathelo amade, kunye ne-reagents esetyenzisiweyo, njenge-malononitrile kunye ne-ethoxymethylene malononitrile, inetyhefu kwaye iyabiza.Ukongezelela, i-3-aminopyrazole-4 elungiselelwe yile ndlela -I-Formamide hemisulfate inombala onzima ukuwususa kwaye ufuna ukuqhutyelwa okongezelelweyo, okunzima kakhulu.

Kukho iingxelo kwiincwadi zangaphandle zisebenzisa i-pyridylamide hydrazone kunye ne-ethoxymethylene malononitrile njengezinto ezibonakalayo zokufumana i-3-amino-4-cyanopyrazole ngokudibanisa kunye ne-cyclization, kwaye emva koko uphendule nge-acid egxininisiweyo ye-sulfuric ukufumana i-compound ekujoliswe kuyo (Reuken G Jones. i-activemethylene compounds [J] J Am Chem Soc. 1952,74 (5): 4889 4891).Izinto eziphambili ezisetyenziswa kule ndlela ziyabiza, isivuno sokusabela asiphezulu, kwaye inzuzo yemveliso yoshishino iphantsi.Kumele ukuba kunzima.

Umgangatho wesiGqeba:Umgangatho woShishino
Umphandle:Umgubo omhlophe okanye omthubi

Umqulu:25kg/igubu
uvavanyo (HPLC) umxholo Omkhulu kuno okanye ulingana no 98.0%
ubumsulwa (HPLC) umxholo Omkhulu kuno okanye ulingana ne 99.5%

Kunikezelwe kulawulo oluluqilima olugqwesileyo kunye nenkampani yabathengi enenkathalo, abasebenzi bethu abanamava abasebenzisana nabo bahlala befumaneka ukuze baxoxe ngeemfuno zakho kwaye benze ulonwabo oluthile lomthengi olupheleleyo lwenkcazo ephezulu Ubonelelo 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, We' ukulungele ukusebenzisana neshishini nabahlobo abalungileyo abavela endlwini yakho naphesheya kweelwandle kwaye wenze ixesha elide elibalaseleyo ngokudibeneyo.
Ingcaciso ephezuluChina Imidazole kunye Imz, Rhoqo ngonyaka, uninzi lwabathengi bethu baya kundwendwela inkampani yethu kwaye bafezekise ukuqhubela phambili kweshishini abasebenza nathi.Siyakwamkela ngokunyanisekileyo ukuba usityelele nangaliphi na ixesha kwaye kunye siya kuphumelela kwimpumelelo enkulu kwishishini leenwele.