Umgangatho omhle 99% 2-Cyanobenzyl Bromide;Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9

Asiyi kuzama kuphela ukubonelela ngeenkampani ezigqwesileyo malunga nomthengi ngamnye, kodwa sikulungele ukufumana naziphi na iingcebiso ezibonelelwa ngabathengi bethu ngomgangatho oMhle 99% 2-Cyanobenzyl Bromide;I-Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Iqela lefemu yethu kunye nokusetyenziswa kobuchwephesha bokusika unikezela ngemveliso ekumgangatho ophezulu ethandwa kakhulu kwaye ixatyiswa ngamathemba ethu kwihlabathi liphela.
Asiyi kuzama kuphela okusemandleni ethu ukunika iinkampani ezigqwesileyo kubo bonke abathengi, kodwa sikulungele ukufumana naziphi na iingcebiso ezinikezelwa ngabathengi bethu.China 2-Cyanobenzyl Bromide Powder kunye neAlpha-Bromo-O-Toluonitrile, Sikholelwa kakhulu ukuba iteknoloji kunye nenkonzo isiseko sethu namhlanje kwaye umgangatho uya kudala iindonga zethu ezithembekileyo zekamva.Kuphela sinomgangatho ongcono kunye nomgangatho ongcono, sinokufezekisa abathengi bethu kunye nathi, ngokunjalo.Wamkelekile abathengi kulo lonke igama ukuba baqhagamshelane nathi ukuze ufumane ishishini ngakumbi kunye nobudlelwane obuthembekileyo.Besisoloko silapha sisebenzela iimfuno zakho nanini na xa ufuna.

Sebenzisa:Phakathi kweLinagliptin.

Sebenzisa:Phakathi kweLinagliptin
Umgangatho wesiGqeba:umgangatho weshishini
Isivavanyi:98-102%

Umphandle:Umgubo omhlophe ukuya kumthubi okhanyayo
Umqulu:25kg/igubu

Ukuhlalutya i-linagliptin ekhoyo kunye nesitshixo sayo esiphakathi kwe-8-bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1--[(4-methyl -2-quinazolinyl)methyl)-1H-purine- I-2,6-dione (11) indlela yokudibanisa, fumana indlela yokwenziwa ilungele imveliso yoshishino.Indlela: shwankathela iindlela ezahlukeneyo zokwenziwa.Iziphumo kunye nezigqibo: Umzila 2.2 unenkqubo elula kunye neendleko eziphantsi, ezifanelekileyo ngakumbi kwimveliso yoshishino.

I-8-bromo-3,7-dihydro-3-methyl-1H-purine-2,6-dione yinto ephambili ephakathi kwi-synthesis ye-hypoglycemic drug linagliptin.I-synthesis ye-1 isebenzisa i-methyl urea kunye ne-cyanoacetic acid njengezinto zokuqala, kwaye ithatha amanyathelo amathandathu e-condensation, i-cyclization, i-nitrosation, ukunciphisa, i-cyclization, kunye ne-bromine kunye nesivuno esipheleleyo se-46.3%.Izakhiwo zabo bonke abaphakathi ziqinisekiswe yi-1HNMR.

Ukuveliswa kwangoku kuhambelana nendlela elula yokulungiselela i-high-purity linagliptin.I-Quinazoline, i-key intermediate yokulungiselela imbiza enye ye-linagliptin 8 bromo 7 (2 butyne 1 base) 3,7 dihydro 3 methyl 1 [(4 methyl 2 quinazolinyl) methyl] 1H Purine 2,6 dione, i-intermediate ihlukaniswe ukuhluzwa, kwaye emva koko yasabela nge-(R)3 aminopiperidine dihydrochloride ukufumana isisombululo esiqulethe i-linagliptin.Emva kokuba isisombululo esiqulathe i-linagliptin sicutshungulwe kwakhona, iDeliraliptin imveliso esulungekileyo.Ukulungiswa kwe-key intermediate ye-invention yangoku yamkela indlela yembiza enye, ekulungele ukusebenza kunye nokuphucula isivuno.Emva kokuba i-intermediate engundoqo ihlulwe, iphendulwa nge (R) i-3 aminopiperidine dihydrochloride, ngaloo ndlela Ukufumana i-linagliptin ephezulu yokucoca iphinda ihlangabezane neemfuno zokuvelisa kunye nokubhengezwa kweenkampani zamachiza ukuya kwinqanaba elikhulu.

Asiyi kuzama kuphela ukubonelela ngeenkampani ezigqwesileyo malunga nomthengi ngamnye, kodwa sikulungele ukufumana naziphi na iingcebiso ezibonelelwa ngabathengi bethu ngomgangatho oMhle 99% 2-Cyanobenzyl Bromide;I-Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Iqela lefemu yethu kunye nokusetyenziswa kobuchwephesha bokusika unikezela ngemveliso ekumgangatho ophezulu ethandwa kakhulu kwaye ixatyiswa ngamathemba ethu kwihlabathi liphela.
Umgangatho olungileyoChina 2-Cyanobenzyl Bromide Powder kunye neAlpha-Bromo-O-Toluonitrile, Sikholelwa kakhulu ukuba iteknoloji kunye nenkonzo isiseko sethu namhlanje kwaye umgangatho uya kudala iindonga zethu ezithembekileyo zekamva.Kuphela sinomgangatho ongcono kunye nomgangatho ongcono, sinokufezekisa abathengi bethu kunye nathi, ngokunjalo.Wamkelekile abathengi kulo lonke igama ukuba baqhagamshelane nathi ukuze ufumane ishishini ngakumbi kunye nobudlelwane obuthembekileyo.Besisoloko silapha sisebenzela iimfuno zakho nanini na xa ufuna.