I-7-ethyl-10-hydroxycamptothecin isetyenziswe njengendawo ephakathi kwe-Irinotecan.
Ichiza le-Irinotecan antitumor.Yi-inhibitor ye-DNA synthesis.Yinto ephuma kwi-semisynthetic ye-camptothecin;Isetyenziselwa ukulungiselela i-irinotecan hydrochloride kunye ne-irinotecan hydrochloride trihydrate;Ulingo olukhulu lwezonyango lubonise ukuba i-irinotecan hydrochloride ineziphumo ezicacileyo zokuthintela kwiintlobo ezahlukeneyo zamathumba, anjengomhlaza wekoloni, umhlaza wemiphunga weseli encinci, umhlaza we-rectal kunye ne-leukemia, kwaye isasebenza kwiimeko ezixhathisa i-fluorouracil.Ke ngoko, i-irinotecan hydrochloride itsale ingqalelo enkulu kwihlabathi liphela.