5,6,7,7a-tetrahydrothieno(3,2-c)pyridine-2(4h)-enye ihydrochloride
5,6,7,7a-tetrahydrothieno(3,2-c)pyridine-2(4h)-enye ihydrochloride
I-5,6,7,7a-tetrahydrothieno (3,2-c) pyridine-2 (4h) -enye i-hydrochloride isetyenziswa njengendawo ephakathi yePrasugrel.
I-Prasugrel yi-thiophenopyridine antiplatelet eyenziwe ngu-Eli Lilly kunye ne-daiichisankyo, umenzi weyeza waseJapan.Lichiza elandulelayo.Yenza i-molecule esebenzayo emva kwe-metabolism ngokusebenzisa i-cytochrome P450 esibindi kwaye idibanisa ne-platelet P2Y12 receptor ukwenza i-active against platelet aggregation.Izifundo zeklinikhi zibonakalise ukuba i-60 mg yedosi inefuthe elingcono le-anticoagulant kune-300 mg yedosi eqhelekileyo kunye ne-600 mg yonyuso lwedosi ye-clopidogrel, enokunciphisa umngcipheko obanzi wokuhlaselwa sisifo sentliziyo, ukubetha kunye nokufa ngenxa yesifo sentliziyo ngama-20%, kwaye inesiphumo esikhawulezayo. , isiphumo esihle sokunyanga, ukunganyangeki kakuhle kweziyobisi kunye ne-bioavailability, kunye netyhefu ephantsi.
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I-TECHNOL OGY I-ADVANTAGES
●Uxinzelelo oluPhezulu lweCatalytic Hydrogenation.Uxinzelelo oluPhezulu lwe-Hydrogenolysis Reaction.I-Cryogenic Reaction (<-78%C)
● I-Aromatic Heterocyclic Synthesis
● Ukusabela ngokutsha
● IsiGqibo seChiral
●Heck, Suzuki,Negishi,Sonogashira .Giignard Reaction
Izixhobo
ILebhu yethu inezixhobo ezahlukeneyo zovavanyo kunye novavanyo, ezifana ne: NMR (Bruker 400M) ,HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, iKhalorimitha yokuSkena okwahlukileyo (DSC), iMicroscope ye-Electron...
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Siye sanceda iinkampani ezininzi eziphezulu zamachiza zasekhaya, ezifanaHansoh, Hengrui kunye ne-HEC Pharm.Apha siza kubonisa inxalenye yazo.
Customization Case One:
Inombolo yeCas: 110351-94-5
Ityala leSibini:
Inombolo yeCas: 144848-24-8
Customization Case Three:
Inombolo yeCas: 200636-54-0
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(R)-(-)-3-Carbamoymethyl-5-methylhexanoic acid
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