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I-2- cyano -5- fluorine benzyl bromide

I-2- cyano -5- fluorine benzyl bromide

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CAS no: 421552-12-7

Iimpawu zeMichiza: iTrelagliptin succinate Intermediates


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Iithegi zeMveliso

Usebenzisa

I-2- cyano -5- fluorine benzyl bromide isetyenziswa njengendawo ephakathi ye-Trelagliptin succinate.
I-Trogliptin succinate sisithinteli se dipeptidyl peptidase Ⅳ (DPP - Ⅳ) ephuhliswe yi-Takeda (Takeda Pharmaceutical Co., Ltd.) eJapan.Inokuthintela ngokukhethayo nangokuqhubekayo iDPP - Ⅳ kwaye ilawule izinga leswekile yegazi.Ulingo lwezonyango lubonisa ukuba ichiza linokhuseleko olululo kunye nokusebenza kakuhle.Kanye ngeveki inokulawula ngokufanelekileyo inqanaba le-glucose yegazi kunye nokuphucula ukuthotyelwa kweyeza kwizigulane.NgoMeyi, 2015, ichiza lamkelwa yi-PMDA yaseJapan ukuba lidweliswe kunyango lwesifo seswekile.


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